A bold typographic composition characteristic of Ruscha's conceptual approach, this photolithograph presents the phrase "Safe and Effective Medication" in stark, matter-of-fact lettering against a plain background. The work plays on the language of pharmaceutical advertising and bureaucratic assurance, transforming familiar vernacular text into an object of quiet irony and scrutiny. Printed in colors on wove paper with full margins, the piece exemplifies Ruscha's enduring fascination with words as images and the loaded power of everyday American language.